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A copper nanoparticle is a copper based particle 1 to 100 nm in size. Like many other forms of nanoparticles, a copper nanoparticle can be formed by natural processes or through chemical synthesis. These nanoparticles are of particular interest due to their historical application as coloring agents and their modern-day biomedical ones. One of the earliest uses of copper nanoparticles was to color glass and ceramics during the ninth century in Mesopotamia. This was done by creating a glaze with copper and silver salts and applying it to clay pottery. When the pottery was baked at high temperatures in reducing conditions, the metal ions migrated to the outer part of the glaze and were reduced to metals.
The end result was a double layer of metal nanoparticles with a small amount of glaze in between them. When the finished pottery was exposed to light, the light would penetrate and reflect off the first layer. The light penetrating the first layer would reflect off the second layer of nanoparticles and cause interference effects with light reflecting off the first layer, creating a luster effect that results from both constructive and destructive interference. Copper nanoparticles with great catalytic activities can be applied to biosensors and electrochemical sensors.
Redox reactions utilized in those sensors are generally irreversible and also require high overpotentials (more energy) to run. In fact, the nanoparticles have the ability to make the redox reactions reversible and to lower the overpotentials when applied to the sensors. A polyacrylamide hydrogel with copper nanoparticles inside is able to determine glucose levels in a sample added to the gel. As phenylboronic acid groups on the hydrogel polymers bind the glucose molecules, the gel becomes swollen. As a result, the copper nanoparticles move apart, changing how incident light is diffracted by the gel. As the glucose levels decrease, the color of gel changes from red to orange to yellow to green.
One of the examples is a glucose sensor. With the use of copper nanoparticles, the sensor does not require any enzyme and therefore has no need to deal with enzyme degradation and denaturation. As described in Figure 3, depending on the level of glucose, the nanoparticles in the sensor diffract the incident light at a different angle. Consequently.
The resulting diffracted light gives a different color based on the level of glucose. In fact, the nanoparticles enable the sensor to be more stable at high temperatures and varying pH, and more resistant to toxic chemicals. Moreover, using nanoparticles, native amino acids can be detected. A copper nanoparticle-plated screen-printed carbon electrode functions as a stable and effective sensing system for all 20 amino acid detection.
Storage Conditions:
Airtight sealed, avoid light and keep dry at room temperature.
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