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8-Arm PEG-succinimidyl carboxyl methyl ester (8-arm PEG-SCM) is a multiarm PEG derivative with succinimidyl NHS ester groups at each terminal of the eight arms connected to one hexaglycerol core. PEG-SCM is one type of PEG-NHS reagents. There is a methylene (CH2) linkage between PEG and the NHS ester. NHS is a good leaving group which can react with amine-containing moities.
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