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Carboxyl methyl-PEG-carboxyl methyl (AA-PEG-AA) is one type of linear bifunctional PEG carboxylic acid reagents. There is a methylene (CH2) linkage between PEG and the COOH group. AA-PEG-AA is also called CM-PEG-CM, CM: carboxyl methyl. PEG acid can be used to react with amine groups with peptide coupling reagents such as NHS and DCC, EDC.
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