신고사유
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Alkyne-polyethylene glycol-maleimide (ALK-PEG-MAL) is a bifunctional PEG derivative that can be used to modify proteins, peptides and other materials via Click Chemistry. Alkyne group can react with azide in aqueous solution catalyzed by copper, and maleimide group can react with thiol group from a peptide. PEGylation can increase solubility and stability and reduce immunogenicity of peptides and proteins. It can also suppress the non-specific binding of charged molecules to the modified surfaces.
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