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BioMag® anti-Human CD IgG-coated particles are produced by covalently attaching murine monoclonal antibodies to BioMag® particles. The antibodies were prepared against human leukocyte differentiation antigens. Each product is supplied in phosphate buffered saline with EDTA and sodium azide added as stabilizers, and should be washed in sterile media prior to use to remove the preservative.
CD45 a major component of the lymphocyte membrane is present on the surface of all human leukocytes, lymphocytes, eosinophils, monocytes, basophils, and neutrophils. In addition, CD45 antibodies react with the leukocyte progenitors found in bone marrow. CD45 is lost during maturation of erythroid cells in the bone marrow and is absent from erythrocytes and platelets.
REQUIRES: Cold Pack
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