신고사유
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Brief Description | Reduces Aβ42 levels; γ-secretase inhibitor; Total Aβ: IC50 = 115 nM (human); Aβ42: IC50 = 200 nM (human) |
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Purity | 0.98 |
Appearance | White solid |
Synonyms | tert-butyl (2S)-2-[[(2S)-2-[[2-(3,5-difluorophenyl)acetyl]amino]propanoyl]amino]-2-phenylacetate; dapt; 208255-80-5; DAPT (GSI-IX); gamma-Secretase Inhibitor IX; CHEBI:86193; MFCD04974585; DAPT, GSI-IX; InSolution™ gamma-Secretase Inhibitor IX; N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester; N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester(DAPT); C23H26F2N2O4; GSIIX; S2215_Selleck; AC1NSKCB; PubChem22436; GSI-IX; DAPT,GSI-IX; DAPT; DAPT - GSI-IX; MLS006010075; CHEMBL255682; QCR-29; SCHEMBL1360313; DTXSID00415519; AOB33372; DAPT-Supplied by Selleck Chemicals; EBD16444; ZINC1549363; ABP000317; ZINC01549363; AKOS024457209; CS-0264; NCGC00167803-03; (3,5-Difluorophenylacetyl)-Ala-Phg-OtBu; AC-23163; AK477268; BC649954; CJ-24363; HY-13027; KB-57235; SMR004701228; AB0033805; LS-191073; D4257; GSI-IX, 208255-80-5; X7572; W-5319; AB01566837_01; GSI-IX , GSI IX; 208255-80-5; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester; DAPT|N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[(3,5-Difluorophenyl)acetyl]-[l-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester; N-[N-(3,5-difluorophenylacetyl)-L-alanyl]-(S)-phenylglycine t-butyl ester |
Solubility | Soluble to 15 mg/mL in DMSO, to ~1 mg/mL in ethanol, in dichloromethane, to ~25 mg/mL in DMF, and to ~0.1 mg/mL in 1:9 solution of DMF:PBS(pH 7.2) |
Storage | Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -24℃ for long term (months to years). |
Application | Differentiation |
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