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Hyaluronic acid (HA) is the most abundant glycosaminoglycan in the body being an important component of several tissues throughout the body. While it is abundant in extracellular matrices, hyaluronan also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions.
HA has carboxylic acid groups that can be used for bioconjugation or further derivatization using amide coupling reaction with primary amines
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