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Poly(D,L-lactide)-block-poly(ethylene glycol)-Biotin (PDLLA-PEG-BIO ) is a functional amphiphilic block copolymer (ABC) which has biotin group at the end of PEG block and is used to prepare nanoparticles and micelles for targeted drug delivery. PLA-PEG is one of the most commonly used biodegradable ABC polymers for drug delivery. Biotin can bind to avidin and streptavidin with high specificity and affinity.
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